The antiproliferative properties and cell death mechanism induced by the extract of the fruits of <em>Luffa echinata </em>Roxb. (LER) were investigated. The methanolic extract of LER inhibited the proliferation of human colon cancer cells (HT-29) in both dose-dependent and time-dependent manners and caused a significant increase in the population of apoptotic cells. https://icemanvideoesgames.shop/product-category/xbox-series-x/