Abstract High-fat diet (HFD)-induced obesity is accompanied by insulin resistance and compromised brain synaptic plasticity through the impairment of insulin-sensitive pathways regulating neuronal survival. learning. and memory. Lipoic acid is known to modulate the redox status of the cell and has insulin mimetic effects. https://www.ashleyshomestores.shop/product-category/6-piece-sectional-with-chaise/